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1brc

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Current revision (15:35, 13 March 2024) (edit) (undo)
 
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[[Image:1brc.png|left|200px]]
 
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{{STRUCTURE_1brc| PDB=1brc | SCENE= }}
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==RELOCATING A NEGATIVE CHARGE IN THE BINDING POCKET OF TRYPSIN==
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<StructureSection load='1brc' size='340' side='right'caption='[[1brc]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===RELOCATING A NEGATIVE CHARGE IN THE BINDING POCKET OF TRYPSIN===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1brc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BRC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BRC FirstGlance]. <br>
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{{ABSTRACT_PUBMED_8478942}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1brc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1brc OCA], [https://pdbe.org/1brc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1brc RCSB], [https://www.ebi.ac.uk/pdbsum/1brc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1brc ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1brc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BRC OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/TRY2_RAT TRY2_RAT]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/1brc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1brc ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Trypsin|Trypsin]]
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*[[Trypsin 3D structures|Trypsin 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:008478942</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Trypsin]]
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[[Category: Fletterick RJ]]
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[[Category: Fletterick, R J.]]
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[[Category: Perona JJ]]
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[[Category: Perona, J J.]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Proteinase]]
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Current revision

RELOCATING A NEGATIVE CHARGE IN THE BINDING POCKET OF TRYPSIN

PDB ID 1brc

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