This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1brv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:35, 13 March 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1brv.png|left|200px]]
 
-
{{STRUCTURE_1brv| PDB=1brv | SCENE= }}
+
==SOLUTION NMR STRUCTURE OF THE IMMUNODOMINANT REGION OF PROTEIN G OF BOVINE RESPIRATORY SYNCYTIAL VIRUS, 48 STRUCTURES==
-
 
+
<StructureSection load='1brv' size='340' side='right'caption='[[1brv]]' scene=''>
-
===SOLUTION NMR STRUCTURE OF THE IMMUNODOMINANT REGION OF PROTEIN G OF BOVINE RESPIRATORY SYNCYTIAL VIRUS, 48 STRUCTURES===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1brv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bovine_respiratory_syncytial_virus_(strain_391-2) Bovine respiratory syncytial virus (strain 391-2)]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BRV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BRV FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_8942628}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1brv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1brv OCA], [https://pdbe.org/1brv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1brv RCSB], [https://www.ebi.ac.uk/pdbsum/1brv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1brv ProSAT]</span></td></tr>
-
==About this Structure==
+
</table>
-
[[1brv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BRV OCA].
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/GLYC_BRSVC GLYC_BRSVC] Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities (By similarity). Secreted glycoprotein G helps RSV escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fcgamma receptors (By similarity).
-
==Reference==
+
== Evolutionary Conservation ==
-
<ref group="xtra">PMID:008942628</ref><references group="xtra"/>
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Viruses]]
+
Check<jmol>
-
[[Category: Boelens, R.]]
+
<jmolCheckbox>
-
[[Category: Doreleijers, J F.]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/1brv_consurf.spt"</scriptWhenChecked>
-
[[Category: Hard, K.]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Kaptein, R.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Langedijk, J P.M.]]
+
</jmolCheckbox>
-
[[Category: Oirschot, J T.Van.]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1brv ConSurf].
-
[[Category: Rullmann, J A.C.]]
+
<div style="clear:both"></div>
-
[[Category: Schaaper, W M.]]
+
__TOC__
-
[[Category: Attachment protein g of bovine respiratory syncytial virus]]
+
</StructureSection>
-
[[Category: Glycoprotein]]
+
[[Category: Large Structures]]
-
[[Category: Immunoglobulin-binding protein]]
+
[[Category: Boelens R]]
-
[[Category: Transmembrane]]
+
[[Category: Doreleijers JF]]
 +
[[Category: Hard K]]
 +
[[Category: Kaptein R]]
 +
[[Category: Langedijk JPM]]
 +
[[Category: Rullmann JAC]]
 +
[[Category: Schaaper WM]]
 +
[[Category: Van Oirschot JT]]

Current revision

SOLUTION NMR STRUCTURE OF THE IMMUNODOMINANT REGION OF PROTEIN G OF BOVINE RESPIRATORY SYNCYTIAL VIRUS, 48 STRUCTURES

PDB ID 1brv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1brv"
Personal tools