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1brv

From Proteopedia

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{{Seed}}
 
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[[Image:1brv.png|left|200px]]
 
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==SOLUTION NMR STRUCTURE OF THE IMMUNODOMINANT REGION OF PROTEIN G OF BOVINE RESPIRATORY SYNCYTIAL VIRUS, 48 STRUCTURES==
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The line below this paragraph, containing "STRUCTURE_1brv", creates the "Structure Box" on the page.
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<StructureSection load='1brv' size='340' side='right'caption='[[1brv]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1brv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bovine_respiratory_syncytial_virus_(strain_391-2) Bovine respiratory syncytial virus (strain 391-2)]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BRV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BRV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1brv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1brv OCA], [https://pdbe.org/1brv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1brv RCSB], [https://www.ebi.ac.uk/pdbsum/1brv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1brv ProSAT]</span></td></tr>
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{{STRUCTURE_1brv| PDB=1brv | SCENE= }}
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</table>
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== Function ==
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===SOLUTION NMR STRUCTURE OF THE IMMUNODOMINANT REGION OF PROTEIN G OF BOVINE RESPIRATORY SYNCYTIAL VIRUS, 48 STRUCTURES===
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[https://www.uniprot.org/uniprot/GLYC_BRSVC GLYC_BRSVC] Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities (By similarity). Secreted glycoprotein G helps RSV escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fcgamma receptors (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_8942628}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 8942628 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/1brv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_8942628}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1brv ConSurf].
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1BRV is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bovine_respiratory_syncytial_virus Bovine respiratory syncytial virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BRV OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:8942628</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Bovine respiratory syncytial virus]]
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[[Category: Boelens R]]
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[[Category: Boelens, R.]]
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[[Category: Doreleijers JF]]
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[[Category: Doreleijers, J F.]]
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[[Category: Hard K]]
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[[Category: Hard, K.]]
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[[Category: Kaptein R]]
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[[Category: Kaptein, R.]]
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[[Category: Langedijk JPM]]
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[[Category: Langedijk, J P.M.]]
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[[Category: Rullmann JAC]]
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[[Category: Oirschot, J T.Van.]]
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[[Category: Schaaper WM]]
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[[Category: Rullmann, J A.C.]]
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[[Category: Van Oirschot JT]]
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[[Category: Schaaper, W M.]]
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[[Category: Attachment protein g of bovine respiratory syncytial virus]]
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[[Category: Glycoprotein]]
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[[Category: Immunoglobulin-binding protein]]
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[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:11:55 2009''
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Current revision

SOLUTION NMR STRUCTURE OF THE IMMUNODOMINANT REGION OF PROTEIN G OF BOVINE RESPIRATORY SYNCYTIAL VIRUS, 48 STRUCTURES

PDB ID 1brv

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