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1btz

From Proteopedia

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{{Seed}}
 
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[[Image:1btz.png|left|200px]]
 
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==Episelection: novel KI ~nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface==
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The line below this paragraph, containing "STRUCTURE_1btz", creates the "Structure Box" on the page.
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<StructureSection load='1btz' size='340' side='right'caption='[[1btz]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1btz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BTZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BTZ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0ZY:N-(TERT-BUTOXYCARBONYL)-L-ALANYL-N-{(1R)-5-AMMONIO-1-[HYDROXY(METHOXY)BORANYL]PENTYL}-L-VALINAMIDE'>0ZY</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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{{STRUCTURE_1btz| PDB=1btz | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1btz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1btz OCA], [https://pdbe.org/1btz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1btz RCSB], [https://www.ebi.ac.uk/pdbsum/1btz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1btz ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRY1_BOVIN TRY1_BOVIN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bt/1btz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1btz ConSurf].
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<div style="clear:both"></div>
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===EPISELECTION: NOVEL KI ~NANOMOLAR INHIBITORS OF SERINE PROTEASES SELECTED BY BINDING OR CHEMISTRY ON AN ENZYME SURFACE===
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==See Also==
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*[[Trypsin 3D structures|Trypsin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_7599119}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 7599119 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7599119}}
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==About this Structure==
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1BTZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BTZ OCA].
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==Reference==
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Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface., Katz BA, Finer-Moore J, Mortezaei R, Rich DH, Stroud RM, Biochemistry. 1995 Jul 4;34(26):8264-80. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7599119 7599119]
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Trypsin]]
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[[Category: Finer-Moore J]]
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[[Category: Finer-Moore, J.]]
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[[Category: Katz BA]]
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[[Category: Katz, B A.]]
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[[Category: Stroud RM]]
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[[Category: Stroud, R M.]]
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[[Category: Tripeptideboronate methyl ester inhibited]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 19:43:06 2008''
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Current revision

Episelection: novel KI ~nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface

PDB ID 1btz

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