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1bus

From Proteopedia

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{{Seed}}
 
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[[Image:1bus.png|left|200px]]
 
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<!--
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==SOLUTION CONFORMATION OF PROTEINASE INHIBITOR IIA FROM BULL SEMINAL PLASMA BY 1H NUCLEAR MAGNETIC RESONANCE AND DISTANCE GEOMETRY==
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The line below this paragraph, containing "STRUCTURE_1bus", creates the "Structure Box" on the page.
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<StructureSection load='1bus' size='340' side='right'caption='[[1bus]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1bus]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BUS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BUS FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
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{{STRUCTURE_1bus| PDB=1bus | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bus OCA], [https://pdbe.org/1bus PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bus RCSB], [https://www.ebi.ac.uk/pdbsum/1bus PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bus ProSAT]</span></td></tr>
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</table>
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===SOLUTION CONFORMATION OF PROTEINASE INHIBITOR IIA FROM BULL SEMINAL PLASMA BY 1H NUCLEAR MAGNETIC RESONANCE AND DISTANCE GEOMETRY===
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== Function ==
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[https://www.uniprot.org/uniprot/ISK6_BOVIN ISK6_BOVIN] Serine protease inhibitor selective for kallikreins. Efficiently inhibits KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14. Doesn't inhibit KLK8. Inhibits acrosin, trypsin, and chymotrypsin.[UniProtKB:Q6UWN8]
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_3839023}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 3839023 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bu/1bus_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_3839023}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1BUS is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BUS OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bus ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:3839023</ref><references group="xtra"/>
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</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Guntert, P.]]
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[[Category: Large Structures]]
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[[Category: Havel, T F.]]
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[[Category: Guntert P]]
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[[Category: Williamson, M P.]]
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[[Category: Havel TF]]
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[[Category: Wuthrich, K.]]
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[[Category: Williamson MP]]
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[[Category: Proteinase inhibitor]]
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[[Category: Wuthrich K]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 12:50:54 2009''
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Current revision

SOLUTION CONFORMATION OF PROTEINASE INHIBITOR IIA FROM BULL SEMINAL PLASMA BY 1H NUCLEAR MAGNETIC RESONANCE AND DISTANCE GEOMETRY

PDB ID 1bus

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