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1cs0

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{{Seed}}
 
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[[Image:1cs0.png|left|200px]]
 
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==Crystal structure of carbamoyl phosphate synthetase complexed at CYS269 in the small subunit with the tetrahedral mimic l-glutamate gamma-semialdehyde==
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The line below this paragraph, containing "STRUCTURE_1cs0", creates the "Structure Box" on the page.
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<StructureSection load='1cs0' size='340' side='right'caption='[[1cs0]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1cs0]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CS0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CS0 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CYG:2-AMINO-4-(AMINO-3-OXO-PROPYLSULFANYLCARBONYL)-BUTYRIC+ACID'>CYG</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NET:TETRAETHYLAMMONIUM+ION'>NET</scene>, <scene name='pdbligand=ORN:L-ORNITHINE'>ORN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_1cs0| PDB=1cs0 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cs0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cs0 OCA], [https://pdbe.org/1cs0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cs0 RCSB], [https://www.ebi.ac.uk/pdbsum/1cs0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cs0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CARB_ECOLI CARB_ECOLI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cs/1cs0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cs0 ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE COMPLEXED AT CYS269 IN THE SMALL SUBUNIT WITH THE TETRAHEDRAL MIMIC L-GLUTAMATE GAMMA-SEMIALDEHYDE===
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==See Also==
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*[[Carbamoyl phosphate synthetase 3D structures|Carbamoyl phosphate synthetase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10587438}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 10587438 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10587438}}
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==About this Structure==
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1CS0 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CS0 OCA].
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==Reference==
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The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway., Thoden JB, Huang X, Raushel FM, Holden HM, Biochemistry. 1999 Dec 7;38(49):16158-66. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10587438 10587438]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Ligase]]
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[[Category: Large Structures]]
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[[Category: Protein complex]]
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[[Category: Holden HM]]
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[[Category: Holden, H M.]]
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[[Category: Huang X]]
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[[Category: Huang, X.]]
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[[Category: Raushel FM]]
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[[Category: Raushel, F M.]]
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[[Category: Thoden JB]]
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[[Category: Thoden, J B.]]
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[[Category: Amidotransferase]]
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[[Category: Substrate channeling]]
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[[Category: Tetrahedral analog]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 21:15:10 2008''
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Current revision

Crystal structure of carbamoyl phosphate synthetase complexed at CYS269 in the small subunit with the tetrahedral mimic l-glutamate gamma-semialdehyde

PDB ID 1cs0

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