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1cus

From Proteopedia

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{{Seed}}
 
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[[Image:1cus.png|left|200px]]
 
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==FUSARIUM SOLANI CUTINASE IS A LIPOLYTIC ENZYME WITH A CATALYTIC SERINE ACCESSIBLE TO SOLVENT==
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The line below this paragraph, containing "STRUCTURE_1cus", creates the "Structure Box" on the page.
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<StructureSection load='1cus' size='340' side='right'caption='[[1cus]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1cus]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Fusarium_vanettenii Fusarium vanettenii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CUS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CUS FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cus OCA], [https://pdbe.org/1cus PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cus RCSB], [https://www.ebi.ac.uk/pdbsum/1cus PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cus ProSAT]</span></td></tr>
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{{STRUCTURE_1cus| PDB=1cus | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CUTI1_FUSVN CUTI1_FUSVN] Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants (PubMed:18658138, PubMed:8286366, PubMed:8555209, PubMed:19810726). Degrades cutin, a macromolecule that forms the structure of the plant cuticle (PubMed:18658138, PubMed:8286366, PubMed:8555209, PubMed:19810726). Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of fungal infection (Ref.4).<ref>PMID:18658138</ref> <ref>PMID:19810726</ref> <ref>PMID:8286366</ref> <ref>PMID:8555209</ref> [PROSITE-ProRule:PRU10109]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cu/1cus_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cus ConSurf].
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<div style="clear:both"></div>
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===FUSARIUM SOLANI CUTINASE IS A LIPOLYTIC ENZYME WITH A CATALYTIC SERINE ACCESSIBLE TO SOLVENT===
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==See Also==
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*[[Cutinase 3D structures|Cutinase 3D structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 1560844 is the PubMed ID number.
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</StructureSection>
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[[Category: Fusarium vanettenii]]
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{{ABSTRACT_PUBMED_1560844}}
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[[Category: Large Structures]]
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[[Category: Cambillau C]]
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==About this Structure==
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[[Category: Martinez C]]
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1CUS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Fusarium_solani_subsp._pisi Fusarium solani subsp. pisi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CUS OCA].
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==Reference==
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Fusarium solani cutinase is a lipolytic enzyme with a catalytic serine accessible to solvent., Martinez C, De Geus P, Lauwereys M, Matthyssens G, Cambillau C, Nature. 1992 Apr 16;356(6370):615-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1560844 1560844]
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[[Category: Fusarium solani subsp. pisi]]
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[[Category: Single protein]]
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[[Category: Cambillau, C.]]
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[[Category: Martinez, C.]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 21:24:05 2008''
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Current revision

FUSARIUM SOLANI CUTINASE IS A LIPOLYTIC ENZYME WITH A CATALYTIC SERINE ACCESSIBLE TO SOLVENT

PDB ID 1cus

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