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1d5b

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{{Seed}}
 
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[[Image:1d5b.png|left|200px]]
 
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<!--
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==UNLIGANDED MATURE OXY-COPE CATALYTIC ANTIBODY==
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The line below this paragraph, containing "STRUCTURE_1d5b", creates the "Structure Box" on the page.
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<StructureSection load='1d5b' size='340' side='right'caption='[[1d5b]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1d5b]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D5B FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
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{{STRUCTURE_1d5b| PDB=1d5b | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d5b OCA], [https://pdbe.org/1d5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d5b RCSB], [https://www.ebi.ac.uk/pdbsum/1d5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d5b ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/IGKC_HUMAN IGKC_HUMAN] Defects in IGKC are the cause of immunoglobulin kappa light chain deficiency (IGKCD) [MIM:[https://omim.org/entry/614102 614102]. IGKCD is a disease characterized by the complete absence of immunoglobulin kappa chains.<ref>PMID:3931219</ref>
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== Function ==
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[https://www.uniprot.org/uniprot/IGKC_HUMAN IGKC_HUMAN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d5/1d5b_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1d5b ConSurf].
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<div style="clear:both"></div>
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===UNLIGANDED MATURE OXY-COPE CATALYTIC ANTIBODY===
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==See Also==
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*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_10651626}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 10651626 is the PubMed ID number.
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</StructureSection>
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-->
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[[Category: Homo sapiens]]
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{{ABSTRACT_PUBMED_10651626}}
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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==About this Structure==
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[[Category: Hanson MA]]
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1D5B is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus_and_homo_sapiens Mus musculus and homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D5B OCA].
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[[Category: Mundorff EC]]
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[[Category: Schultz PG]]
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==Reference==
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[[Category: Stevens RC]]
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<ref group="xtra">PMID:10651626</ref><references group="xtra"/>
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[[Category: Mus musculus and homo sapiens]]
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[[Category: Hanson, M A.]]
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[[Category: Mundorff, E C.]]
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[[Category: Schultz, P G.]]
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[[Category: Stevens, R C.]]
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[[Category: Immune system]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:20:04 2009''
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Current revision

UNLIGANDED MATURE OXY-COPE CATALYTIC ANTIBODY

PDB ID 1d5b

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