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3q5l
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==Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K 213 in the presence of 17-AEP-geldanamycin== | ==Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K 213 in the presence of 17-AEP-geldanamycin== | ||
| - | <StructureSection load='3q5l' size='340' side='right' caption='[[3q5l]], [[Resolution|resolution]] 2.65Å' scene=''> | + | <StructureSection load='3q5l' size='340' side='right'caption='[[3q5l]], [[Resolution|resolution]] 2.65Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3q5l]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3q5l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q5L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q5L FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KX2:(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-HYDROXY-8,14-DIMETHOXY-4,10,12,16-TETRAMETHYL-3,20,22-TRIOXO-19-{[2-(PYRROLIDIN-1-YL)ETHYL]AMINO}-2-AZABICYCLO[16.3.1]DOCOSA-1(21),4,6,10,18-PENTAEN-9-YL+CARBAMATE'>KX2</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KX2:(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-HYDROXY-8,14-DIMETHOXY-4,10,12,16-TETRAMETHYL-3,20,22-TRIOXO-19-{[2-(PYRROLIDIN-1-YL)ETHYL]AMINO}-2-AZABICYCLO[16.3.1]DOCOSA-1(21),4,6,10,18-PENTAEN-9-YL+CARBAMATE'>KX2</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q5l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q5l OCA], [https://pdbe.org/3q5l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q5l RCSB], [https://www.ebi.ac.uk/pdbsum/3q5l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q5l ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q4Q4I6_LEIMA Q4Q4I6_LEIMA] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Heat Shock Protein structures|Heat Shock Protein structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Arrowsmith | + | [[Category: Leishmania major]] |
| - | [[Category: Bountra | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Cossar | + | [[Category: Bountra C]] |
| - | [[Category: Edwards | + | [[Category: Cossar D]] |
| - | [[Category: Fairlamb | + | [[Category: Edwards AM]] |
| - | [[Category: Ferguson | + | [[Category: Fairlamb A]] |
| - | [[Category: Hills | + | [[Category: Ferguson MAJ]] |
| - | [[Category: Hui | + | [[Category: Hills T]] |
| - | [[Category: Hutchinson | + | [[Category: Hui R]] |
| - | [[Category: Lin | + | [[Category: Hutchinson A]] |
| - | [[Category: MacKenzie | + | [[Category: Lin YH]] |
| - | [[Category: Pizarro | + | [[Category: MacKenzie F]] |
| - | + | [[Category: Pizarro JC]] | |
| - | [[Category: Schapira | + | [[Category: Schapira M]] |
| - | [[Category: Tempel | + | [[Category: Tempel W]] |
| - | [[Category: Weigelt | + | [[Category: Weigelt J]] |
| - | [[Category: Wernimont | + | [[Category: Wernimont AK]] |
| - | [[Category: Zhao | + | [[Category: Zhao Y]] |
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Current revision
Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K 213 in the presence of 17-AEP-geldanamycin
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Categories: Large Structures | Leishmania major | Arrowsmith CH | Bountra C | Cossar D | Edwards AM | Fairlamb A | Ferguson MAJ | Hills T | Hui R | Hutchinson A | Lin YH | MacKenzie F | Pizarro JC | Schapira M | Tempel W | Weigelt J | Wernimont AK | Zhao Y
