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3q8f
From Proteopedia
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| - | [[Image:3q8f.png|left|200px]] | ||
| - | + | ==Crystal structure of 2-Fluorohistine labeled Protective Antigen (pH 5.8)== | |
| - | + | <StructureSection load='3q8f' size='340' side='right'caption='[[3q8f]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3q8f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q8F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q8F FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |
| - | == | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2HF:2-FLUORO-L-HISTIDINE'>2HF</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> |
| - | [[3q8f]] is a 1 chain structure | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q8f OCA], [https://pdbe.org/3q8f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q8f RCSB], [https://www.ebi.ac.uk/pdbsum/3q8f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q8f ProSAT]</span></td></tr> |
| - | + | </table> | |
| - | == | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/PAG_BACAN PAG_BACAN] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax. | |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Bacillus anthracis]] | [[Category: Bacillus anthracis]] | ||
| - | [[Category: Andra | + | [[Category: Large Structures]] |
| - | [[Category: Bann | + | [[Category: Andra KK]] |
| - | [[Category: Battaile | + | [[Category: Bann JG]] |
| - | [[Category: Janowiak | + | [[Category: Battaile KP]] |
| - | [[Category: Lovell | + | [[Category: Janowiak BE]] |
| - | [[Category: Rajapaksha | + | [[Category: Lovell S]] |
| - | + | [[Category: Rajapaksha M]] | |
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Current revision
Crystal structure of 2-Fluorohistine labeled Protective Antigen (pH 5.8)
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