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3qk3
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==Crystal structure of human beta-crystallin B3== | ==Crystal structure of human beta-crystallin B3== | ||
| - | <StructureSection load='3qk3' size='340' side='right' caption='[[3qk3]], [[Resolution|resolution]] 1.95Å' scene=''> | + | <StructureSection load='3qk3' size='340' side='right'caption='[[3qk3]], [[Resolution|resolution]] 1.95Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3qk3]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3qk3]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QK3 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qk3 OCA], [https://pdbe.org/3qk3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qk3 RCSB], [https://www.ebi.ac.uk/pdbsum/3qk3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qk3 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/CRBB3_HUMAN CRBB3_HUMAN] Non-syndromic congenital cataract. Cataract, congenital, nuclear, autosomal recessive 2 (CATCN2) [MIM:[https://omim.org/entry/609741 609741]: A congenital cataract affecting the central nucleus of the eye. Nucler cataracts are often not highly visually significant. The density of the opacities varies greatly from fine dots to a dense, white and chalk-like, central cataract. The condition is usually bilateral. Nuclear cataracts are often combined with opacified cortical fibers encircling the nuclear opacity, which are referred to as cortical riders. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:15914629</ref> |
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/CRBB3_HUMAN CRBB3_HUMAN] Crystallins are the dominant structural components of the vertebrate eye lens. |
| + | |||
| + | ==See Also== | ||
| + | *[[Crystallin 3D structures|Crystallin 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| - | [[Category: | + | [[Category: Cocking R]] |
| - | [[Category: Edwards | + | [[Category: Edwards A]] |
| - | [[Category: Gileadi | + | [[Category: Gileadi C]] |
| - | [[Category: Kavanagh | + | [[Category: Kavanagh K]] |
| - | [[Category: Krojer | + | [[Category: Krojer T]] |
| - | [[Category: Muniz | + | [[Category: Muniz J]] |
| - | [[Category: Oppermann | + | [[Category: Oppermann U]] |
| - | [[Category: Pike | + | [[Category: Pike ACW]] |
| - | [[Category: Pilka | + | [[Category: Pilka E]] |
| - | + | [[Category: Vollmar M]] | |
| - | [[Category: Vollmar | + | [[Category: Weigelt J]] |
| - | [[Category: Weigelt | + | [[Category: Yue WW]] |
| - | [[Category: Yue | + | [[Category: Von Delft F]] |
| - | [[Category: | + | |
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Current revision
Crystal structure of human beta-crystallin B3
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Cocking R | Edwards A | Gileadi C | Kavanagh K | Krojer T | Muniz J | Oppermann U | Pike ACW | Pilka E | Vollmar M | Weigelt J | Yue WW | Von Delft F
