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3qmc
From Proteopedia
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| - | {{STRUCTURE_3qmc| PDB=3qmc | SCENE= }} | ||
| - | ===Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1=== | ||
| - | {{ABSTRACT_PUBMED_21407193}} | ||
| - | == | + | ==Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1== |
| - | [[ | + | <StructureSection load='3qmc' size='340' side='right'caption='[[3qmc]], [[Resolution|resolution]] 2.10Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[3qmc]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QMC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QMC FirstGlance]. <br> |
| - | [[3qmc]] is a 3 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qmc OCA], [https://pdbe.org/3qmc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qmc RCSB], [https://www.ebi.ac.uk/pdbsum/3qmc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qmc ProSAT]</span></td></tr> |
| - | < | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CXXC1_HUMAN CXXC1_HUMAN] Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.<ref>PMID:21407193</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
| - | [[Category: Bian | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bochkarev | + | [[Category: Bian CB]] |
| - | [[Category: Bountra | + | [[Category: Bochkarev A]] |
| - | [[Category: Edwards | + | [[Category: Bountra C]] |
| - | [[Category: Kania | + | [[Category: Edwards AM]] |
| - | [[Category: Lam | + | [[Category: Kania J]] |
| - | [[Category: Min | + | [[Category: Lam R]] |
| - | + | [[Category: Min J]] | |
| - | [[Category: Weigelt | + | [[Category: Weigelt J]] |
| - | [[Category: Xu | + | [[Category: Xu C]] |
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Current revision
Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bian CB | Bochkarev A | Bountra C | Edwards AM | Kania J | Lam R | Min J | Weigelt J | Xu C
