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3qs7
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of a human Flt3 ligand-receptor ternary complex== | |
| + | <StructureSection load='3qs7' size='340' side='right'caption='[[3qs7]], [[Resolution|resolution]] 4.30Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3qs7]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QS7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QS7 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.3Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qs7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qs7 OCA], [https://pdbe.org/3qs7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qs7 RCSB], [https://www.ebi.ac.uk/pdbsum/3qs7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qs7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FLT3L_HUMAN FLT3L_HUMAN] Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. | ||
| - | + | ==See Also== | |
| - | + | *[[Tyrosine kinase 3D structures|Tyrosine kinase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Savvides SN]] | ||
| + | [[Category: Verstraete K]] | ||
Current revision
Crystal structure of a human Flt3 ligand-receptor ternary complex
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