3r0i

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'''Unreleased structure'''
 
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The entry 3r0i is ON HOLD until Paper Publication
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==IspC in complex with an N-methyl-substituted hydroxamic acid==
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<StructureSection load='3r0i' size='340' side='right'caption='[[3r0i]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3r0i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R0I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R0I FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C0K:{(1S)-1-(3,4-DIFLUOROPHENYL)-4-[HYDROXY(METHYL)AMINO]-4-OXOBUTYL}PHOSPHONIC+ACID'>C0K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r0i OCA], [https://pdbe.org/3r0i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r0i RCSB], [https://www.ebi.ac.uk/pdbsum/3r0i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r0i ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DXR_ECOLI DXR_ECOLI] Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).[HAMAP-Rule:MF_00183]
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Authors: Behrendt, C.T., Kunfermann, A., Illarionova, V., Matheeussen, A., Pein, M.K., Graewert, T., Bacher, A., Eisenreich, W., Illarionov, B., Fischer, M., Maes, L., Groll, M., Kurz, T.
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==See Also==
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*[[DXP reductoisomerase 3D Structures|DXP reductoisomerase 3D Structures]]
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Description: IspC in complex with an N-methyl-substituted hydroxamic acid
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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[[Category: Bacher A]]
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[[Category: Behrendt CT]]
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[[Category: Eisenreich W]]
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[[Category: Fischer M]]
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[[Category: Graewert T]]
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[[Category: Groll M]]
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[[Category: Illarionov B]]
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[[Category: Illarionova V]]
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[[Category: Kunfermann A]]
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[[Category: Kurz T]]
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[[Category: Maes L]]
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[[Category: Matheeussen A]]
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[[Category: Pein MK]]

Current revision

IspC in complex with an N-methyl-substituted hydroxamic acid

PDB ID 3r0i

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