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3r4x

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==Crystal structure of bovine lactoperoxidase complexed with pyrazine-2-carboxamide at 2 A resolution==
==Crystal structure of bovine lactoperoxidase complexed with pyrazine-2-carboxamide at 2 A resolution==
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<StructureSection load='3r4x' size='340' side='right' caption='[[3r4x]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
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<StructureSection load='3r4x' size='340' side='right'caption='[[3r4x]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3r4x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R4X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3R4X FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3r4x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R4X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R4X FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PZA:PYRAZINE-2-CARBOXAMIDE'>PZA</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PZA:PYRAZINE-2-CARBOXAMIDE'>PZA</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3gc1|3gc1]], [[3r55|3r55]], [[3r5o|3r5o]], [[3r5q|3r5q]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r4x OCA], [https://pdbe.org/3r4x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r4x RCSB], [https://www.ebi.ac.uk/pdbsum/3r4x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r4x ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peroxidase Peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.7 1.11.1.7] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3r4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r4x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3r4x RCSB], [http://www.ebi.ac.uk/pdbsum/3r4x PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PERL_BOVIN PERL_BOVIN] LPO is an antimicrobial agent. It is thought to help protect the udder from infection and promote growth in newborn calves.
==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Peroxidase]]
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[[Category: Large Structures]]
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[[Category: Kaur, P]]
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[[Category: Kaur P]]
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[[Category: Pandey, N]]
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[[Category: Pandey N]]
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[[Category: Sharma, S]]
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[[Category: Sharma S]]
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[[Category: Singh, A K]]
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[[Category: Singh AK]]
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[[Category: Singh, R P]]
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[[Category: Singh RP]]
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[[Category: Singh, T P]]
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[[Category: Singh TP]]
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[[Category: Sinha, M]]
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[[Category: Sinha M]]
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[[Category: Bovine lactoperoxidase]]
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[[Category: Iodide]]
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[[Category: Oxidoreductase]]
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[[Category: Peg]]
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[[Category: Phenyl isothiocyanate]]
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[[Category: Pyrazinamide]]
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Current revision

Crystal structure of bovine lactoperoxidase complexed with pyrazine-2-carboxamide at 2 A resolution

PDB ID 3r4x

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