This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3r5k

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:11, 14 March 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3r5k.jpg|left|200px]]
 
-
<!--
+
==A designed redox-controlled caspase-7==
-
The line below this paragraph, containing "STRUCTURE_3r5k", creates the "Structure Box" on the page.
+
<StructureSection load='3r5k' size='340' side='right'caption='[[3r5k]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3r5k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R5K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R5K FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.86&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
-
{{STRUCTURE_3r5k| PDB=3r5k | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r5k OCA], [https://pdbe.org/3r5k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r5k RCSB], [https://www.ebi.ac.uk/pdbsum/3r5k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r5k ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CASP7_HUMAN CASP7_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.
-
===A designed redox-controlled caspase-7===
+
==See Also==
-
 
+
*[[Caspase 3D structures|Caspase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_21674661}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 21674661 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_21674661}}
+
-
 
+
-
==About this Structure==
+
-
[[3r5k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R5K OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:021674661</ref><references group="xtra"/>
+
-
[[Category: Caspase-7]]
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Hardy, J A.]]
+
[[Category: Large Structures]]
-
[[Category: Witkowski, W A.]]
+
[[Category: Hardy JA]]
-
[[Category: Apoptosis]]
+
[[Category: Witkowski WA]]
-
[[Category: Caspase]]
+
-
[[Category: Cystine aspartate protease]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Protease]]
+
-
[[Category: Thiol protease]]
+
-
[[Category: Zymogen]]
+

Current revision

A designed redox-controlled caspase-7

PDB ID 3r5k

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3r5k"
Personal tools