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3rab
From Proteopedia
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| - | {{STRUCTURE_3rab| PDB=3rab | SCENE= }} | ||
| - | ===GPPNHP-BOUND RAB3A AT 2.0 A RESOLUTION=== | ||
| - | {{ABSTRACT_PUBMED_10196122}} | ||
| - | == | + | ==GPPNHP-BOUND RAB3A AT 2.0 A RESOLUTION== |
| - | [[http://www.uniprot.org/uniprot/RAB3A_RAT RAB3A_RAT | + | <StructureSection load='3rab' size='340' side='right'caption='[[3rab]], [[Resolution|resolution]] 2.00Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3rab]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RAB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RAB FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rab OCA], [https://pdbe.org/3rab PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rab RCSB], [https://www.ebi.ac.uk/pdbsum/3rab PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rab ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RAB3A_RAT RAB3A_RAT] Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ra/3rab_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3rab ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | < | + | [[Category: Large Structures]] |
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| - | [[Category: Connolly | + | [[Category: Connolly JL]] |
| - | [[Category: Dumas | + | [[Category: Dumas JJ]] |
| - | [[Category: Lambright | + | [[Category: Lambright DG]] |
| - | [[Category: Zhu | + | [[Category: Zhu Z]] |
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Current revision
GPPNHP-BOUND RAB3A AT 2.0 A RESOLUTION
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