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3rgt

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Current revision (12:23, 14 March 2024) (edit) (undo)
 
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<StructureSection load='3rgt' size='340' side='right'caption='[[3rgt]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3rgt' size='340' side='right'caption='[[3rgt]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3rgt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_baa-138 Atcc baa-138]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RGT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RGT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3rgt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Chromohalobacter_salexigens Chromohalobacter salexigens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RGT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RGT FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EZ4:(2S,3R,4R)-2,3,4,5-TETRAHYDROXY-N-OXO-PENTANAMIDE'>EZ4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3ow1|3ow1]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EZ4:(2S,3R,4R)-2,3,4,5-TETRAHYDROXY-N-OXO-PENTANAMIDE'>EZ4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Csal_2974 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158080 ATCC BAA-138])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Mannonate_dehydratase Mannonate dehydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.8 4.2.1.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rgt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rgt OCA], [https://pdbe.org/3rgt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rgt RCSB], [https://www.ebi.ac.uk/pdbsum/3rgt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rgt ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rgt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rgt OCA], [https://pdbe.org/3rgt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rgt RCSB], [https://www.ebi.ac.uk/pdbsum/3rgt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rgt ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DMGD_CHRSD DMGD_CHRSD] Has low dehydratase activity with D-mannonate and D-gluconate, suggesting that these are not physiological substrates and that it has no significant role in the in vivo degradation of these compounds. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc baa-138]]
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[[Category: Chromohalobacter salexigens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Mannonate dehydratase]]
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[[Category: Almo SC]]
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[[Category: Almo, S C]]
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[[Category: Fedorov AA]]
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[[Category: Fedorov, A A]]
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[[Category: Fedorov EV]]
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[[Category: Fedorov, E V]]
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[[Category: Gerlt JA]]
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[[Category: Gerlt, J A]]
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[[Category: Wichelecki D]]
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[[Category: Wichelecki, D]]
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[[Category: D-arabinohydroxamate]]
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[[Category: D-mannonate dehydratase]]
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[[Category: Enolase fold]]
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[[Category: Lyase]]
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Current revision

Crystal structure of d-mannonate dehydratase from Chromohalobacter salexigens complexed with D-Arabinohydroxamate

PDB ID 3rgt

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