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3rvn

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==Structure of the CheY-BeF3 Complex with substitutions at 59 and 89: N59D and E89Y==
==Structure of the CheY-BeF3 Complex with substitutions at 59 and 89: N59D and E89Y==
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<StructureSection load='3rvn' size='340' side='right' caption='[[3rvn]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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<StructureSection load='3rvn' size='340' side='right'caption='[[3rvn]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3rvn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RVN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RVN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3rvn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RVN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RVN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fqw|1fqw]], [[3rvk|3rvk]], [[3rvl|3rvl]], [[3rvm|3rvm]], [[3rvj|3rvj]], [[3rvo|3rvo]], [[3rvp|3rvp]], [[3rvq|3rvq]], [[3rvr|3rvr]], [[3rvs|3rvs]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b1882, cheY, JW1871 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rvn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rvn OCA], [https://pdbe.org/3rvn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rvn RCSB], [https://www.ebi.ac.uk/pdbsum/3rvn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rvn ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rvn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rvn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rvn RCSB], [http://www.ebi.ac.uk/pdbsum/3rvn PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CHEY_ECOLI CHEY_ECOLI]] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Overexpression of CheY in association with MotA and MotB improves motility of a ycgR disruption, suggesting there is an interaction (direct or indirect) between the c-di-GMP-binding flagellar brake protein and the flagellar stator.<ref>PMID:20346719</ref>
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[https://www.uniprot.org/uniprot/CHEY_ECOLI CHEY_ECOLI] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Overexpression of CheY in association with MotA and MotB improves motility of a ycgR disruption, suggesting there is an interaction (direct or indirect) between the c-di-GMP-binding flagellar brake protein and the flagellar stator.<ref>PMID:20346719</ref>
==See Also==
==See Also==
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*[[Chemotaxis protein|Chemotaxis protein]]
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*[[Chemotaxis protein 3D structures|Chemotaxis protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Bourret, R B]]
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[[Category: Large Structures]]
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[[Category: Immormino, R M]]
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[[Category: Bourret RB]]
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[[Category: Silversmith, R E]]
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[[Category: Immormino RM]]
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[[Category: Starbird, C A]]
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[[Category: Silversmith RE]]
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[[Category: Beta-alpha protein]]
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[[Category: Starbird CA]]
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[[Category: Chea chez chex]]
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[[Category: Chemotaxis]]
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[[Category: Chey]]
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[[Category: Phosphorylation]]
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[[Category: Response regulator]]
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[[Category: Signal transduction]]
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[[Category: Signaling protein]]
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[[Category: Two-component]]
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Current revision

Structure of the CheY-BeF3 Complex with substitutions at 59 and 89: N59D and E89Y

PDB ID 3rvn

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