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3rxw
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==KPC-2 carbapenemase in complex with PSR3-226== | |
| + | <StructureSection load='3rxw' size='340' side='right'caption='[[3rxw]], [[Resolution|resolution]] 1.26Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3rxw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. The July 2015 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''New Delhi Metallo-b-Lactamase'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2015_7 10.2210/rcsb_pdb/mom_2015_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RXW FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.26Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=SR3:(2S,3R)-4-(2-AMINO-2-OXOETHOXY)-3-(DIHYDROXY-LAMBDA~4~-SULFANYL)-3-METHYL-4-OXO-2-{[(1E)-3-OXOPROP-1-EN-1-YL]AMINO}BUTANOIC+ACID'>SR3</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rxw OCA], [https://pdbe.org/3rxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rxw RCSB], [https://www.ebi.ac.uk/pdbsum/3rxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rxw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BLKPC_KLEPN BLKPC_KLEPN] Hydrolyzes carbapenems, penicillins, cephalosporins and monobactams with varying efficiency. | ||
| - | + | ==See Also== | |
| - | + | *[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Klebsiella pneumoniae]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: New Delhi Metallo-b-Lactamase]] | ||
| + | [[Category: RCSB PDB Molecule of the Month]] | ||
| + | [[Category: Ke W]] | ||
| + | [[Category: Van den Akker F]] | ||
Current revision
KPC-2 carbapenemase in complex with PSR3-226
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