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3s0n

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[[Image:3s0n.png|left|200px]]
 
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==Crystal Structure of Human Chymase with Benzimidazolone Inhibitor==
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The line below this paragraph, containing "STRUCTURE_3s0n", creates the "Structure Box" on the page.
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<StructureSection load='3s0n' size='340' side='right'caption='[[3s0n]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3s0n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S0N FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0BB:4-{3-[(4-METHYL-1-BENZOTHIOPHEN-3-YL)METHYL]-2-OXO-2,3-DIHYDRO-1H-BENZIMIDAZOL-1-YL}BUTANOIC+ACID'>0BB</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_3s0n| PDB=3s0n | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s0n OCA], [https://pdbe.org/3s0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s0n RCSB], [https://www.ebi.ac.uk/pdbsum/3s0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s0n ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of Human Chymase with Benzimidazolone Inhibitor===
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== Function ==
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[https://www.uniprot.org/uniprot/CMA1_HUMAN CMA1_HUMAN] Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 21733690 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21733690}}
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==About this Structure==
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[[3s0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S0N OCA].
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==Reference==
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<ref group="xtra">PMID:021733690</ref><references group="xtra"/>
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[[Category: Chymase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Farrow, N A.]]
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[[Category: Large Structures]]
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[[Category: Padyana, A K.]]
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[[Category: Farrow NA]]
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[[Category: Qian, K C.]]
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[[Category: Padyana AK]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Qian KC]]
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[[Category: Serine protease]]
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Current revision

Crystal Structure of Human Chymase with Benzimidazolone Inhibitor

PDB ID 3s0n

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