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3s5v

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[[Image:3s5v.png|left|200px]]
 
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==Structure of the cyanobacterial Oscillatoria Agardhii Agglutinin (OAA) in free state obtained at -180 degrees Celsius==
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The line below this paragraph, containing "STRUCTURE_3s5v", creates the "Structure Box" on the page.
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<StructureSection load='3s5v' size='340' side='right'caption='[[3s5v]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3s5v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Planktothrix_agardhii Planktothrix agardhii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S5V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S5V FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3s5v| PDB=3s5v | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s5v OCA], [https://pdbe.org/3s5v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s5v RCSB], [https://www.ebi.ac.uk/pdbsum/3s5v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s5v ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LEC1_PLAAG LEC1_PLAAG] Lectin specific for high mannose N-glycans, recognizes the branched moiety of these glycans. Does not recognize other types of N-glycans or monosaccharides. Agglutinates trypsin-treated rabbit erythrocytes. Does not require divalent cations for activity. Inhibits HIV replication in MT4 cells with an EC(50) of 45 nM. Binds to the HIV envelope glycoprotein gp120.<ref>PMID:10817903</ref> <ref>PMID:17314091</ref>
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===Structure of the cyanobacterial Oscillatoria Agardhii Agglutinin (OAA) in free state obtained at -180 degrees Celsius===
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==See Also==
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*[[Agglutinin 3D structures|Agglutinin 3D structures]]
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== References ==
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 21827952 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_21827952}}
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==About this Structure==
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[[3s5v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Planktothrix_agardhii Planktothrix agardhii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S5V OCA].
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==Reference==
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<ref group="xtra">PMID:021827952</ref><ref group="xtra">PMID:020961847</ref><references group="xtra"/>
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[[Category: Planktothrix agardhii]]
[[Category: Planktothrix agardhii]]
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[[Category: Gronenborn, A M.]]
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[[Category: Gronenborn AM]]
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[[Category: Koharudin, L M.I.]]
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[[Category: Koharudin LMI]]
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[[Category: Anti-hiv lectin]]
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[[Category: Beta barrel like fold]]
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[[Category: Carbohydrate]]
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[[Category: Protein binding]]
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Current revision

Structure of the cyanobacterial Oscillatoria Agardhii Agglutinin (OAA) in free state obtained at -180 degrees Celsius

PDB ID 3s5v

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