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3s9e

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[[Image:3s9e.png|left|200px]]
 
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==Crystal structure of the kainate receptor GluK3 ligand binding domain in complex with (S)-glutamate==
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The line below this paragraph, containing "STRUCTURE_3s9e", creates the "Structure Box" on the page.
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<StructureSection load='3s9e' size='340' side='right'caption='[[3s9e]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3s9e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S9E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S9E FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_3s9e| PDB=3s9e | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s9e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s9e OCA], [https://pdbe.org/3s9e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s9e RCSB], [https://www.ebi.ac.uk/pdbsum/3s9e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s9e ProSAT]</span></td></tr>
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</table>
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===Crystal structure of the kainate receptor GluK3 ligand binding domain in complex with (S)-glutamate===
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== Function ==
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[https://www.uniprot.org/uniprot/GRIK3_RAT GRIK3_RAT] Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA.<ref>PMID:21907808</ref>
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(as it appears on PubMed at http://www.pubmed.gov), where 21907808 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21907808}}
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==About this Structure==
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[[3s9e]] is a 2 chain structure of [[Ionotropic Glutamate Receptors]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S9E OCA].
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==See Also==
==See Also==
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*[[Ionotropic Glutamate Receptors|Ionotropic Glutamate Receptors]]
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*[[Glutamate receptor 3D structures|Glutamate receptor 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:021907808</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Frydenvang, K.]]
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[[Category: Frydenvang K]]
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[[Category: Gajhede, M.]]
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[[Category: Gajhede M]]
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[[Category: Kastrup, J S.]]
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[[Category: Kastrup JS]]
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[[Category: Venskutonyte, R.]]
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[[Category: Venskutonyte R]]
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[[Category: Agonist]]
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[[Category: Glutamate]]
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[[Category: Ionotropic glutamate receptor]]
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[[Category: Membrane]]
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[[Category: Membrane protein]]
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Current revision

Crystal structure of the kainate receptor GluK3 ligand binding domain in complex with (S)-glutamate

PDB ID 3s9e

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