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3sao
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3sao is ON HOLD Authors: Correnti, C. Description: The Siderocalin Ex-FABP functions through dual ligand specificities) |
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The Siderocalin Ex-FABP functions through dual ligand specificities== |
| + | <StructureSection load='3sao' size='340' side='right'caption='[[3sao]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3sao]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SAO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SAO FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DBH:2,3-DIHYDROXY-BENZOIC+ACID'>DBH</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NKN:(2R)-2-HYDROXY-3-(PHOSPHONOOXY)PROPYL+TETRADECANOATE'>NKN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sao OCA], [https://pdbe.org/3sao PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sao RCSB], [https://www.ebi.ac.uk/pdbsum/3sao PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sao ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/EXFAB_CHICK EXFAB_CHICK] Siderocalin-like lipocalin tightly binding a variety of bacterial ferric siderophores, also binds long-chain unsaturated fatty acids such as linoleic acid, oleic acid, arachidonic acid and, with a lower affinity, long chain saturated fatty acids such as steraic acid. May act as an antibacterial factor, through dual ligand specificity, both as a siderophore-sequestrating molecule and a lysophosphatidic acid (LPA) sensor. | ||
| - | + | ==See Also== | |
| - | + | *[[Siderocalin 3D structures|Siderocalin 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Gallus gallus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Clifton MC]] | ||
| + | [[Category: Correnti C]] | ||
| + | [[Category: Strong RK]] | ||
Current revision
The Siderocalin Ex-FABP functions through dual ligand specificities
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