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3sjq

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[[Image:3sjq.jpg|left|200px]]
 
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==Crystal structure of a small conductance potassium channel splice variant complexed with calcium-calmodulin==
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The line below this paragraph, containing "STRUCTURE_3sjq", creates the "Structure Box" on the page.
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<StructureSection load='3sjq' size='340' side='right'caption='[[3sjq]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3sjq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SJQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SJQ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PHU:1-PHENYLUREA'>PHU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3sjq| PDB=3sjq | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sjq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sjq OCA], [https://pdbe.org/3sjq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sjq RCSB], [https://www.ebi.ac.uk/pdbsum/3sjq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sjq ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CALM1_RAT CALM1_RAT] Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Mediates calcium-dependent inactivation of CACNA1C. Positively regulates calcium-activated potassium channel activity of KCNN2.[UniProtKB:P62158]
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===Crystal structure of a small conductance potassium channel splice variant complexed with calcium-calmodulin===
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==See Also==
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*[[Calmodulin 3D structures|Calmodulin 3D structures]]
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*[[Potassium channel 3D structures|Potassium channel 3D structures]]
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 22579256 is the PubMed ID number.
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_22579256}}
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==About this Structure==
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[[3sjq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SJQ OCA].
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==Reference==
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<ref group="xtra">PMID:022579256</ref><references group="xtra"/>
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[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Pascal, J M.]]
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[[Category: Pascal JM]]
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[[Category: Zhang, J F.]]
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[[Category: Zhang J-F]]
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[[Category: Zhang, M.]]
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[[Category: Zhang M]]
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[[Category: Calcium binding]]
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[[Category: Calmodulin]]
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[[Category: Ef hand]]
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[[Category: Metal binding protein]]
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[[Category: Protein-protein complex]]
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Current revision

Crystal structure of a small conductance potassium channel splice variant complexed with calcium-calmodulin

PDB ID 3sjq

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