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3smj
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Human poly(ADP-ribose) polymerase 14 (Parp14/Artd8) - catalytic domain in complex with a pyrimidine-like inhibitor== | |
| + | <StructureSection load='3smj' size='340' side='right'caption='[[3smj]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3smj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SMJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SMJ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FDR:2-METHYL-3,5,6,7-TETRAHYDRO-4H-CYCLOPENTA[4,5]THIENO[2,3-D]PYRIMIDIN-4-ONE'>FDR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3smj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3smj OCA], [https://pdbe.org/3smj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3smj RCSB], [https://www.ebi.ac.uk/pdbsum/3smj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3smj ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PAR14_HUMAN PAR14_HUMAN] Enhances STAT6-dependent transcription (By similarity). Has ADP-ribosyltransferase activity. | ||
| - | + | ==See Also== | |
| - | + | *[[Poly(ADP-ribose) polymerase 3D structures|Poly(ADP-ribose) polymerase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Berglund H]] | ||
| + | [[Category: Bountra C]] | ||
| + | [[Category: Edwards AM]] | ||
| + | [[Category: Ekblad T]] | ||
| + | [[Category: Graslund S]] | ||
| + | [[Category: Karlberg T]] | ||
| + | [[Category: Kouznetsova E]] | ||
| + | [[Category: Moche M]] | ||
| + | [[Category: Nordlund P]] | ||
| + | [[Category: Nyman T]] | ||
| + | [[Category: Schuler H]] | ||
| + | [[Category: Thorsell AG]] | ||
| + | [[Category: Tresaugues L]] | ||
| + | [[Category: Weigelt J]] | ||
Current revision
Human poly(ADP-ribose) polymerase 14 (Parp14/Artd8) - catalytic domain in complex with a pyrimidine-like inhibitor
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Berglund H | Bountra C | Edwards AM | Ekblad T | Graslund S | Karlberg T | Kouznetsova E | Moche M | Nordlund P | Nyman T | Schuler H | Thorsell AG | Tresaugues L | Weigelt J
