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3snf
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Onconase, atomic resolution crystal structure== | |
| - | + | <StructureSection load='3snf' size='340' side='right'caption='[[3snf]], [[Resolution|resolution]] 1.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3snf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lithobates_pipiens Lithobates pipiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SNF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SNF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3snf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3snf OCA], [https://pdbe.org/3snf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3snf RCSB], [https://www.ebi.ac.uk/pdbsum/3snf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3snf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RNP30_LITPI RNP30_LITPI] Basic protein with antiproliferative/cytotoxic activity against several tumor cell lines in vitro, as well as antitumor in vivo. It exhibits a ribonuclease-like activity against high molecular weight ribosomal RNA. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lithobates pipiens]] | ||
| + | [[Category: Acharya KR]] | ||
| + | [[Category: Holloway DE]] | ||
| + | [[Category: Shogen K]] | ||
| + | [[Category: Singh UP]] | ||
Current revision
Onconase, atomic resolution crystal structure
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