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3spj

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[[Image:3spj.png|left|200px]]
 
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{{STRUCTURE_3spj| PDB=3spj | SCENE= }}
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==Apo inward rectifier potassium channel Kir2.2 I223L mutant==
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<StructureSection load='3spj' size='340' side='right'caption='[[3spj]], [[Resolution|resolution]] 3.31&Aring;' scene=''>
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===Apo inward rectifier potassium channel Kir2.2 I223L mutant===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3spj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SPJ FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21874019}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.307&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3spj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3spj OCA], [https://pdbe.org/3spj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3spj RCSB], [https://www.ebi.ac.uk/pdbsum/3spj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3spj ProSAT]</span></td></tr>
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[[3spj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPJ OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KCJ12_CHICK KCJ12_CHICK] Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. The inward rectification is probably due to the blockage of outward current by cytoplasmic polyamines and/or magnesium ions.<ref>PMID:20019282</ref> <ref>PMID:21874019</ref>
==See Also==
==See Also==
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*[[Potassium Channel|Potassium Channel]]
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*[[Potassium channel 3D structures|Potassium channel 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:021874019</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Hansen, S B.]]
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[[Category: Large Structures]]
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[[Category: MacKinnon, R.]]
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[[Category: Hansen SB]]
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[[Category: Tao, X.]]
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[[Category: MacKinnon R]]
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[[Category: Lipid]]
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[[Category: Tao X]]
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[[Category: Membrane protein]]
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[[Category: Metal transport]]
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[[Category: Pip]]
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[[Category: Receptor]]
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Current revision

Apo inward rectifier potassium channel Kir2.2 I223L mutant

PDB ID 3spj

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