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3sqp

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[[Image:3sqp.png|left|200px]]
 
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{{STRUCTURE_3sqp| PDB=3sqp | SCENE= }}
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==Structure of human glutathione reductase complexed with pyocyanin, an agent with antimalarial activity==
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<StructureSection load='3sqp' size='340' side='right'caption='[[3sqp]], [[Resolution|resolution]] 2.21&Aring;' scene=''>
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===Structure of human glutathione reductase complexed with pyocyanin, an agent with antimalarial activity===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3sqp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SQP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SQP FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21888766}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.21&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3J8:5-METHYLPHENAZIN-1(5H)-ONE'>3J8</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sqp OCA], [https://pdbe.org/3sqp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sqp RCSB], [https://www.ebi.ac.uk/pdbsum/3sqp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sqp ProSAT]</span></td></tr>
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[[3sqp]] is a 2 chain structure of [[Glutathione Reductase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SQP OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GSHR_HUMAN GSHR_HUMAN] Maintains high levels of reduced glutathione in the cytosol.
==See Also==
==See Also==
*[[Glutathione Reductase|Glutathione Reductase]]
*[[Glutathione Reductase|Glutathione Reductase]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021888766</ref><references group="xtra"/>
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[[Category: Glutathione-disulfide reductase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Fritz-Wolf, K.]]
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[[Category: Large Structures]]
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[[Category: Goebel, U.]]
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[[Category: Fritz-Wolf K]]
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[[Category: Koenig, I.]]
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[[Category: Goebel U]]
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[[Category: Schirmer, R H.]]
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[[Category: Koenig I]]
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[[Category: Alternative initiation]]
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[[Category: Schirmer RH]]
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[[Category: Cellular reductant]]
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[[Category: Flavoprotein]]
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[[Category: Glutathione reductase]]
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[[Category: Mitochondrion]]
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[[Category: Oxidoreductase]]
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[[Category: Oxidoreductase-antibiotic complex]]
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[[Category: Phosphoprotein]]
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[[Category: Plasmodium falciparum]]
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[[Category: Pyocyanin]]
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[[Category: Redox-active center]]
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[[Category: Transit peptide]]
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Current revision

Structure of human glutathione reductase complexed with pyocyanin, an agent with antimalarial activity

PDB ID 3sqp

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