This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3ssx
From Proteopedia
(Difference between revisions)
| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:3ssx.png|left|200px]] | ||
| - | + | ==E. coli trp aporeporessor L75F mutant== | |
| - | + | <StructureSection load='3ssx' size='340' side='right'caption='[[3ssx]], [[Resolution|resolution]] 1.58Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3ssx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SSX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SSX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5801Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TAM:TRIS(HYDROXYETHYL)AMINOMETHANE'>TAM</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ssx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ssx OCA], [https://pdbe.org/3ssx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ssx RCSB], [https://www.ebi.ac.uk/pdbsum/3ssx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ssx ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | |
| - | + | __TOC__ | |
| - | == | + | </StructureSection> |
| - | [[3ssx]] is a 2 chain structure with sequence from [ | + | [[Category: Escherichia coli K-12]] |
| - | [[ | + | [[Category: Large Structures]] |
| - | [[ | + | [[Category: Benoff B]] |
| - | [[ | + | [[Category: Berman HM]] |
| - | [[Category: | + | [[Category: Carey J]] |
| - | [[Category: | + | [[Category: Lawson CL]] |
| - | [[Category: | + | |
| - | [[Category: | + | |
| - | [[Category: | + | |
| - | [[Category: | + | |
Current revision
E. coli trp aporeporessor L75F mutant
| |||||||||||
