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3t0o
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3t0o is ON HOLD Authors: Thorn, A., Kraetzner, R., Steinfeld, R., Sheldrick, G. Description: Crystal Structure Analysis of Human RNase T2) |
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| - | '''Unreleased structure''' | ||
| - | The entry | + | ==Crystal Structure Analysis of Human RNase T2== |
| + | <StructureSection load='3t0o' size='340' side='right'caption='[[3t0o]], [[Resolution|resolution]] 1.59Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3t0o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T0O FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.59Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t0o OCA], [https://pdbe.org/3t0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t0o RCSB], [https://www.ebi.ac.uk/pdbsum/3t0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t0o ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/RNT2_HUMAN RNT2_HUMAN] Cystic leukoencephalopathy without megalencephaly. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RNT2_HUMAN RNT2_HUMAN] Has ribonuclease activity, with higher activity at acidic pH. Probably is involved in lysosomal degradation of ribosomal RNA (By similarity). Probably plays a role in cellular RNA catabolism.<ref>PMID:16620762</ref> <ref>PMID:19525954</ref> <ref>PMID:22735700</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Ribonuclease 3D structures|Ribonuclease 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Kraetzner R]] | ||
| + | [[Category: Sheldrick G]] | ||
| + | [[Category: Steinfeld R]] | ||
| + | [[Category: Thorn A]] | ||
Current revision
Crystal Structure Analysis of Human RNase T2
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