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3t2g
From Proteopedia
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| - | [[Image:3t2g.png|left|200px]] | ||
| - | + | ==Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, Y229F variant with DHAP== | |
| - | + | <StructureSection load='3t2g' size='340' side='right'caption='[[3t2g]], [[Resolution|resolution]] 3.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3t2g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrobaculum_neutrophilum_V24Sta Pyrobaculum neutrophilum V24Sta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T2G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T2G FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=13P:1,3-DIHYDROXYACETONEPHOSPHATE'>13P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t2g OCA], [https://pdbe.org/3t2g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t2g RCSB], [https://www.ebi.ac.uk/pdbsum/3t2g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t2g ProSAT]</span></td></tr> |
| - | [[3t2g]] is a 1 chain structure | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FBPAP_PYRNV FBPAP_PYRNV] Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).<ref>PMID:20348906</ref> <ref>PMID:21983965</ref> | ||
==See Also== | ==See Also== | ||
| - | *[[Aldolase|Aldolase]] | + | *[[Aldolase 3D structures|Aldolase 3D structures]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Du | + | [[Category: Large Structures]] |
| - | [[Category: Einsle | + | [[Category: Pyrobaculum neutrophilum V24Sta]] |
| - | [[Category: Fuchs | + | [[Category: Du J]] |
| - | [[Category: Lue | + | [[Category: Einsle O]] |
| - | [[Category: Say | + | [[Category: Fuchs G]] |
| - | + | [[Category: Lue W]] | |
| - | + | [[Category: Say R]] | |
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Current revision
Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, Y229F variant with DHAP
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