3t7n
From Proteopedia
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| - | [[Image:3t7n.png|left|200px]] | ||
| - | + | ==Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and UDP, in a monoclinic closed form== | |
| - | + | <StructureSection load='3t7n' size='340' side='right'caption='[[3t7n]], [[Resolution|resolution]] 1.98Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3t7n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T7N FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.98Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t7n OCA], [https://pdbe.org/3t7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t7n RCSB], [https://www.ebi.ac.uk/pdbsum/3t7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t7n ProSAT]</span></td></tr> |
| - | [[3t7n]] is a 2 chain structure with sequence from [ | + | </table> |
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/GLYG_HUMAN GLYG_HUMAN] Glycogen storage disease due to glycogenin deficiency. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GLYG_HUMAN GLYG_HUMAN] Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. | ||
==See Also== | ==See Also== | ||
*[[Glycogenin|Glycogenin]] | *[[Glycogenin|Glycogenin]] | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| - | [[Category: | + | [[Category: Chaikuad A]] |
| - | [[Category: Edwards | + | [[Category: Edwards AM]] |
| - | [[Category: Froese | + | [[Category: Froese DS]] |
| - | [[Category: Krysztofinska | + | [[Category: Krysztofinska E]] |
| - | [[Category: Oppermann | + | [[Category: Oppermann U]] |
| - | + | [[Category: Weigelt J]] | |
| - | [[Category: Weigelt | + | [[Category: Yue WW]] |
| - | [[Category: Yue | + | [[Category: Von Delft F]] |
| - | [[Category: | + | |
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Current revision
Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and UDP, in a monoclinic closed form
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