This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.

3tby

From Proteopedia

(Difference between revisions)

Jump to: navigation, search

Current revision

CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH THE LCMV-DERIVED GP33 ALTERED PEPTIDE ligand (V3P, Y4F)

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3tby"

@@ Line 1: / Line 1: @@
 ==CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH THE LCMV-DERIVED GP33 ALTERED PEPTIDE ligand (V3P, Y4F)==
-<StructureSection load='3tby' size='340' side='right' caption='[[3tby]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
+<StructureSection load='3tby' size='340' side='right'caption='[[3tby]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3tby]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TBY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TBY FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3tby]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Lymphocytic_choriomeningitis_virus_(strain_WE) Lymphocytic choriomeningitis virus (strain WE)] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TBY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TBY FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1s7u|1s7u]], [[1s7v|1s7v]], [[1s7w|1s7w]], [[1s7x|1s7x]], [[3qul|3qul]], [[3quk|3quk]], [[3tbs|3tbs]], [[3tbt|3tbt]], [[3tbv|3tbv]], [[3tbw|3tbw]], [[3tbx|3tbx]]</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tby OCA], [http://pdbe.org/3tby PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3tby RCSB], [http://www.ebi.ac.uk/pdbsum/3tby PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3tby ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tby OCA], [https://pdbe.org/3tby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tby RCSB], [https://www.ebi.ac.uk/pdbsum/3tby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tby ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/HA11_MOUSE HA11_MOUSE]] Involved in the presentation of foreign antigens to the immune system. [[http://www.uniprot.org/uniprot/GLYC_LYCVW GLYC_LYCVW]] The stable signal peptide (SSP) is cleaved and functions as a signal peptide. In addition, it is apparently retained as the third component of the GP complex. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of GP1 and GP2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion (By similarity).  Glycoprotein G1 mediates virus attachment to host receptor alpha-dystroglycan DAG1. This attachment induces virion internalization predominantly through clathrin- and caveolin-independent endocytosis (By similarity).  Glycoprotein G2 is a viral fusion protein. Membrane fusion is mediated by conformational changes induced upon acidification in the endosome (Potential). [[http://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
+[https://www.uniprot.org/uniprot/HA11_MOUSE HA11_MOUSE] Involved in the presentation of foreign antigens to the immune system.
 ==See Also==
-*[[Beta-2 microglobulin|Beta-2 microglobulin]]
+*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
-*[[Major histocompatibility complex|Major histocompatibility complex]]
+*[[MHC 3D structures|MHC 3D structures]]
+*[[MHC I 3D structures|MHC I 3D structures]]
 __TOC__
 </StructureSection>
-[[Category: Achour, A]]
+[[Category: Large Structures]]
-[[Category: Allerbring, E B]]
+[[Category: Mus musculus]]
-[[Category: Badia-Martinez, D]]
+[[Category: Achour A]]
-[[Category: Duru, A D]]
+[[Category: Allerbring EB]]
-[[Category: Madhurantakam, C]]
+[[Category: Badia-Martinez D]]
-[[Category: Mazumdar, P A]]
+[[Category: Duru AD]]
-[[Category: Nygren, P]]
+[[Category: Madhurantakam C]]
-[[Category: Sandalova, T]]
+[[Category: Mazumdar PA]]
-[[Category: Uchtenhagen, H]]
+[[Category: Nygren P]]
-[[Category: Agonism]]
+[[Category: Sandalova T]]
-[[Category: Altered peptide ligand]]
+[[Category: Uchtenhagen H]]
-[[Category: Antagonism]]
-[[Category: Antigen presentation]]
-[[Category: Beta2-microglobulin]]
-[[Category: Cd8]]
-[[Category: Cell surface]]
-[[Category: Immune system]]
-[[Category: Immune system-agonist complex]]
-[[Category: Lcmv]]
-[[Category: Murine mhc]]
-[[Category: Receptor binding]]
-[[Category: T cell receptor]]
-[[Category: T cell recognition]]

3tby

From Proteopedia

Current revision

CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH THE LCMV-DERIVED GP33 ALTERED PEPTIDE ligand (V3P, Y4F)

Structural highlights

Function

See Also

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

Personal tools

Navigation

Search

Toolbox