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3tob

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[[Image:3tob.jpg|left|200px]]
 
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==Human MOF E350Q crystal structure with active site lysine partially acetylated==
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The line below this paragraph, containing "STRUCTURE_3tob", creates the "Structure Box" on the page.
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<StructureSection load='3tob' size='340' side='right'caption='[[3tob]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3tob]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TOB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TOB FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.703&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_3tob| PDB=3tob | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tob OCA], [https://pdbe.org/3tob PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tob RCSB], [https://www.ebi.ac.uk/pdbsum/3tob PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tob ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KAT8_HUMAN KAT8_HUMAN] Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. That activity is less specific than the one of the MSL complex.<ref>PMID:12397079</ref> <ref>PMID:15923642</ref> <ref>PMID:20018852</ref>
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===Human MOF E350Q crystal structure with active site lysine partially acetylated===
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==See Also==
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*[[Histone acetyltransferase 3D structures|Histone acetyltransferase 3D structures]]
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== References ==
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 22020126 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_22020126}}
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==About this Structure==
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[[3tob]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TOB OCA].
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==Reference==
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<ref group="xtra">PMID:022020126</ref><references group="xtra"/>
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[[Category: Histone acetyltransferase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Ding, E C.]]
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[[Category: Large Structures]]
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[[Category: Marmorstein, R.]]
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[[Category: Ding EC]]
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[[Category: Yuan, H.]]
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[[Category: Marmorstein R]]
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[[Category: Hat domain]]
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[[Category: Yuan H]]
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[[Category: Myst protein]]
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[[Category: Transferase]]
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[[Category: Zinc finger]]
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Current revision

Human MOF E350Q crystal structure with active site lysine partially acetylated

PDB ID 3tob

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