This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3tr5
From Proteopedia
(Difference between revisions)
| (7 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:3tr5.jpg|left|200px]] | ||
| - | + | ==Structure of a peptide chain release factor 3 (prfC) from Coxiella burnetii== | |
| - | + | <StructureSection load='3tr5' size='340' side='right'caption='[[3tr5]], [[Resolution|resolution]] 2.11Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3tr5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Coxiella_burnetii Coxiella burnetii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TR5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.11Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tr5 OCA], [https://pdbe.org/3tr5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tr5 RCSB], [https://www.ebi.ac.uk/pdbsum/3tr5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tr5 ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/RF3_COXBU RF3_COXBU] Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.[HAMAP-Rule:MF_00072] | |
| - | + | __TOC__ | |
| - | == | + | </StructureSection> |
| - | [[3tr5]] is a 4 chain structure with sequence from [ | + | |
[[Category: Coxiella burnetii]] | [[Category: Coxiella burnetii]] | ||
| - | [[Category: Burshteyn | + | [[Category: Large Structures]] |
| - | [[Category: Cassidy | + | [[Category: Burshteyn F]] |
| - | [[Category: Cheung | + | [[Category: Cassidy M]] |
| - | [[Category: Franklin | + | [[Category: Cheung J]] |
| - | [[Category: Gary | + | [[Category: Franklin MC]] |
| - | [[Category: Love | + | [[Category: Gary E]] |
| - | [[Category: Rudolph | + | [[Category: Love J]] |
| - | + | [[Category: Rudolph M]] | |
| - | + | ||
Current revision
Structure of a peptide chain release factor 3 (prfC) from Coxiella burnetii
| |||||||||||
Categories: Coxiella burnetii | Large Structures | Burshteyn F | Cassidy M | Cheung J | Franklin MC | Gary E | Love J | Rudolph M
