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3tw1

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[[Image:3tw1.png|left|200px]]
 
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{{STRUCTURE_3tw1| PDB=3tw1 | SCENE= }}
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==Structure of Rtt106-AHN==
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<StructureSection load='3tw1' size='340' side='right'caption='[[3tw1]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
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===Structure of Rtt106-AHN===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3tw1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TW1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TW1 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_22307274}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.772&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AHN:N-[2-(1H-IMIDAZOL-4-YL)ETHYL]ACETAMIDE'>AHN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tw1 OCA], [https://pdbe.org/3tw1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tw1 RCSB], [https://www.ebi.ac.uk/pdbsum/3tw1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tw1 ProSAT]</span></td></tr>
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[[3tw1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TW1 OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/RT106_YEAST RT106_YEAST] Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by directly recruiting the SWI/SNF and RSC chromatin remodeling complexes to the histone genes in a cell cycle dependent manner. In cooperation with HIR and ASF1, creates a repressive structure at the core histone gene promoter and contributes to their repression outside of S phase. Involved in regulation of Ty1 transposition.<ref>PMID:11779788</ref> <ref>PMID:16157874</ref> <ref>PMID:17410207</ref> <ref>PMID:19683497</ref> <ref>PMID:20188666</ref> <ref>PMID:21763693</ref> <ref>PMID:22156209</ref> <ref>PMID:21444721</ref> <ref>PMID:21698254</ref> <ref>PMID:21978826</ref> <ref>PMID:22128187</ref> <ref>PMID:20007951</ref>
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<ref group="xtra">PMID:022307274</ref><references group="xtra"/>
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== References ==
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[[Category: Saccharomyces cerevisiae]]
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<references/>
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[[Category: Mer, G.]]
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__TOC__
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[[Category: Su, D.]]
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</StructureSection>
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[[Category: Thompson, J R.]]
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[[Category: Large Structures]]
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[[Category: Chaperone]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Chromosomal protein]]
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[[Category: Mer G]]
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[[Category: Nucleus]]
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[[Category: Su D]]
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[[Category: Phosphoprotein]]
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[[Category: Thompson JR]]
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[[Category: Tandem pleckstrin-homology domain]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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Current revision

Structure of Rtt106-AHN

PDB ID 3tw1

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