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3u33
From Proteopedia
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| - | [[Image:3u33.png|left|200px]] | ||
| - | + | ==Crystal Structure of the E. coli adaptive response protein AidB in the space group P3(2)== | |
| - | + | <StructureSection load='3u33' size='340' side='right'caption='[[3u33]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3u33]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U33 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U33 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u33 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u33 OCA], [https://pdbe.org/3u33 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u33 RCSB], [https://www.ebi.ac.uk/pdbsum/3u33 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u33 ProSAT]</span></td></tr> |
| - | [[3u33]] is a 12 chain structure with sequence from [ | + | </table> |
| - | + | == Function == | |
| - | == | + | [https://www.uniprot.org/uniprot/AIDB_ECOLI AIDB_ECOLI] Part of the adaptive DNA-repair response to alkylating agents. Could prevent alkylation damage by protecting DNA and destroying alkylating agents that have yet to reach their DNA target. Binds to double-stranded DNA with a preference for a DNA region that includes its own promoter. Shows weak isovaleryl-CoA dehydrogenase activity in vitro.<ref>PMID:7961409</ref> <ref>PMID:16352838</ref> <ref>PMID:18829440</ref> |
| - | < | + | == References == |
| - | [[ | + | <references/> |
| - | [ | + | __TOC__ |
| - | [ | + | </StructureSection> |
| - | [ | + | [[Category: Escherichia coli K-12]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Drennan CL]] |
| - | [[Category: | + | [[Category: Jost M]] |
| - | [[Category: | + | [[Category: Wong C]] |
| - | [[Category: | + | |
Current revision
Crystal Structure of the E. coli adaptive response protein AidB in the space group P3(2)
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