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3uic

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[[Image:3uic.png|left|200px]]
 
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{{STRUCTURE_3uic| PDB=3uic | SCENE= }}
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==Crystal Structure of FabI, an Enoyl Reductase from F. tularensis, in complex with a Novel and Potent Inhibitor==
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<StructureSection load='3uic' size='340' side='right'caption='[[3uic]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===Crystal Structure of FabI, an Enoyl Reductase from F. tularensis, in complex with a Novel and Potent Inhibitor===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3uic]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Francisella_tularensis_subsp._tularensis Francisella tularensis subsp. tularensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UIC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UIC FirstGlance]. <br>
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{{ABSTRACT_PUBMED_22642319}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=09T:1-(3,4-DICHLOROBENZYL)-5,6-DIMETHYL-1H-BENZIMIDAZOLE'>09T</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uic OCA], [https://pdbe.org/3uic PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uic RCSB], [https://www.ebi.ac.uk/pdbsum/3uic PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uic ProSAT]</span></td></tr>
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[[3uic]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Francisella_tularensis_subsp._tularensis Francisella tularensis subsp. tularensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UIC OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5NGQ3_FRATT Q5NGQ3_FRATT]
==See Also==
==See Also==
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*[[Enoyl-Acyl-Carrier Protein Reductase|Enoyl-Acyl-Carrier Protein Reductase]]
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*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]]
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__TOC__
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</StructureSection>
[[Category: Francisella tularensis subsp. tularensis]]
[[Category: Francisella tularensis subsp. tularensis]]
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[[Category: Johnson, M E.]]
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[[Category: Large Structures]]
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[[Category: Mehboob, S.]]
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[[Category: Johnson ME]]
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[[Category: Santarsiero, B D.]]
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[[Category: Mehboob S]]
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[[Category: Truong, K.]]
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[[Category: Santarsiero BD]]
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[[Category: Enoyl reductase]]
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[[Category: Truong K]]
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[[Category: Nadh binding]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
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[[Category: Rossmann fold]]
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Current revision

Crystal Structure of FabI, an Enoyl Reductase from F. tularensis, in complex with a Novel and Potent Inhibitor

PDB ID 3uic

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