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3uo3
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Jac1 co-chaperone from Saccharomyces cerevisiae, 5-182 clone== | |
| - | + | <StructureSection load='3uo3' size='340' side='right'caption='[[3uo3]], [[Resolution|resolution]] 1.85Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3uo3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UO3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UO3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uo3 OCA], [https://pdbe.org/3uo3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uo3 RCSB], [https://www.ebi.ac.uk/pdbsum/3uo3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uo3 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/JAC1_YEAST JAC1_YEAST] Co-chaperone required for the assembly of iron-sulfur (Fe/S) clusters in mitochondria. Stimulates the ATPase activity of its specialized Hsp70 chaperone partner SSQ1. Binds to the substrate protein ISU1 and targets it to SSQ1. May function together with SSQ1 in the dislocation of the Fe/S cluster from ISU1 and its insertion into apoproteins.<ref>PMID:11171977</ref> <ref>PMID:9813017</ref> <ref>PMID:11278728</ref> <ref>PMID:11273703</ref> <ref>PMID:12970193</ref> <ref>PMID:12756240</ref> <ref>PMID:15123690</ref> <ref>PMID:16431909</ref> <ref>PMID:16551614</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Babnigg G]] | ||
| + | [[Category: Bigelow L]] | ||
| + | [[Category: Craig EA]] | ||
| + | [[Category: Dutkiewicz R]] | ||
| + | [[Category: Feldmann B]] | ||
| + | [[Category: Joachimiak A]] | ||
| + | [[Category: Marszalek J]] | ||
| + | [[Category: Mulligan R]] | ||
| + | [[Category: Osipiuk J]] | ||
Current revision
Jac1 co-chaperone from Saccharomyces cerevisiae, 5-182 clone
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