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3up5
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3up5 is ON HOLD Authors: Shi, R., Matte, A., Cygler, M., Lau, P. Description: Crystal Structure of OTEMO complex with FAD and NADP (form 4)) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of OTEMO complex with FAD and NADP (form 4)== | |
| - | + | <StructureSection load='3up5' size='340' side='right'caption='[[3up5]], [[Resolution|resolution]] 2.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3up5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UP5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UP5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.453Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3up5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3up5 OCA], [https://pdbe.org/3up5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3up5 RCSB], [https://www.ebi.ac.uk/pdbsum/3up5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3up5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/OTEMO_PSEPU OTEMO_PSEPU] Involved in the degradation of (+)-camphor. Catalyzes the lactonization of 2-oxo-delta(3)-4,5, 5-trimethylcyclopentenylacetyl-CoA (OT-CoA), a key intermediate in the metabolism of camphor. 2-Oxocyclopentyl ethyl acetate is also a good substrate, as is 2-oxocyclohexyl ethyl acetate and methyl-substituted cyclohexanones, but free acid is a poor substrate.<ref>PMID:22267661</ref> <ref>PMID:22286514</ref> <ref>PMID:6848481</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pseudomonas putida]] | ||
| + | [[Category: Cygler M]] | ||
| + | [[Category: Lau P]] | ||
| + | [[Category: Matte A]] | ||
| + | [[Category: Shi R]] | ||
Current revision
Crystal Structure of OTEMO complex with FAD and NADP (form 4)
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