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3urk

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[[Image:3urk.png|left|200px]]
 
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{{STRUCTURE_3urk| PDB=3urk | SCENE= }}
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==IspH in complex with propynyl diphosphate (1061)==
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<StructureSection load='3urk' size='340' side='right'caption='[[3urk]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3urk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3URK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3URK FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0CG:PROP-2-YN-1-YL+TRIHYDROGEN+DIPHOSPHATE'>0CG</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3urk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3urk OCA], [https://pdbe.org/3urk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3urk RCSB], [https://www.ebi.ac.uk/pdbsum/3urk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3urk ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ISPH_ECOLI ISPH_ECOLI] Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Is also involved in penicillin tolerance and control of the stringent response. Seems to directly or indirectly interact with RelA to maintain it in an inactive form during normal growth.<ref>PMID:19569147</ref> <ref>PMID:20080550</ref> <ref>PMID:22137895</ref>
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===IspH in complex with propynyl diphosphate (1061)===
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==See Also==
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*[[4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3D structures|4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3D structures]]
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{{ABSTRACT_PUBMED_22948824}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[3urk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3URK OCA].
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</StructureSection>
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[[Category: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase]]
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[[Category: Escherichia coli K-12]]
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[[Category: Escherichia coli]]
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[[Category: Large Structures]]
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[[Category: Bacher, A.]]
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[[Category: Bacher A]]
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[[Category: Eisenreich, W.]]
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[[Category: Eisenreich W]]
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[[Category: Groll, M.]]
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[[Category: Groll M]]
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[[Category: Oldfield, E.]]
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[[Category: Oldfield E]]
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[[Category: Schulz, C.]]
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[[Category: Schulz C]]
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[[Category: Span, I.]]
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[[Category: Span I]]
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[[Category: Wang, K.]]
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[[Category: Wang K]]
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[[Category: Wang, W.]]
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[[Category: Wang W]]
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[[Category: Zhang, Y.]]
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[[Category: Zhang Y]]
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[[Category: Iron-sulfur protein]]
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[[Category: Isoprenoid biosynthesis]]
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[[Category: Isph]]
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[[Category: Lytb]]
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[[Category: Non-mevalonate pathway]]
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[[Category: Oxidoreductase]]
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Current revision

IspH in complex with propynyl diphosphate (1061)

PDB ID 3urk

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