This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3v7d

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:20, 14 March 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3v7d.jpg|left|200px]]
 
-
<!--
+
==Crystal Structure of ScSkp1-ScCdc4-pSic1 peptide complex==
-
The line below this paragraph, containing "STRUCTURE_3v7d", creates the "Structure Box" on the page.
+
<StructureSection load='3v7d' size='340' side='right'caption='[[3v7d]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3v7d]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V7D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V7D FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.306&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
-
{{STRUCTURE_3v7d| PDB=3v7d | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v7d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v7d OCA], [https://pdbe.org/3v7d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v7d RCSB], [https://www.ebi.ac.uk/pdbsum/3v7d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v7d ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal Structure of ScSkp1-ScCdc4-pSic1 peptide complex===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/SKP1_YEAST SKP1_YEAST] Essential component of the E3 ubiquitin ligase complex SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins like phosphorylated SIC1. Participates in the attachment of chromosomes to the spindle. Acts as a regulatory component of the centromere DNA-binding protein complex CBF3, which is essential for chromosome segregation and movement of centromeres along microtubules. CBF3 is required for the recruitment of other kinetochore complexes to CEN DNA. It plays a role in the attachment of chromosomes to the spindle and binds selectively to a highly conserved DNA sequence called CDEIII, found in centromeres and in several promoters. The association of CBF3C with CBF3D and SGT1 is required for CBF3C activation and CBF3 assembly. SKP1/CBF3D could retrieve cyclins or cyclin-CDK-like proteins into the kinetochore thus providing cell cycle-regulated kinetochore activity. Involved in the regulation of methionine biosynthesis genes. Facilitates association of CDC53 with CDC4 and of ROY1 with YPT52.<ref>PMID:8706132</ref> <ref>PMID:8706131</ref> <ref>PMID:9346238</ref> <ref>PMID:9346239</ref> <ref>PMID:21389113</ref> <ref>PMID:9499404</ref> <ref>PMID:17517885</ref>
-
 
+
== References ==
-
<!--
+
<references/>
-
The line below this paragraph, {{ABSTRACT_PUBMED_22328159}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 22328159 is the PubMed ID number.
+
</StructureSection>
-
-->
+
[[Category: Large Structures]]
-
{{ABSTRACT_PUBMED_22328159}}
+
[[Category: Saccharomyces cerevisiae S288C]]
-
 
+
[[Category: Csizmok V]]
-
==About this Structure==
+
[[Category: Forman-Kay J]]
-
[[3v7d]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V7D OCA].
+
[[Category: Mittag T]]
-
 
+
[[Category: Orlicky S]]
-
==Reference==
+
[[Category: Pawson T]]
-
<ref group="xtra">PMID:022328159</ref><references group="xtra"/>
+
[[Category: Sicheri F]]
-
[[Category: Saccharomyces cerevisiae]]
+
[[Category: Tang X]]
-
[[Category: Csizmok, V.]]
+
[[Category: Tyers M]]
-
[[Category: Forman-Kay, J.]]
+
-
[[Category: Mittag, T.]]
+
-
[[Category: Orlicky, S.]]
+
-
[[Category: Pawson, T.]]
+
-
[[Category: Sicheri, F.]]
+
-
[[Category: Tang, X.]]
+
-
[[Category: Tyers, M.]]
+
-
[[Category: Cell cycle]]
+
-
[[Category: E3 ubiquitin ligase]]
+
-
[[Category: Ligase]]
+
-
[[Category: Phospho binding protein]]
+
-
[[Category: Phospho-peptide complex]]
+
-
[[Category: Phosphorylation]]
+
-
[[Category: Sic1]]
+
-
[[Category: Wd 40 domain]]
+

Current revision

Crystal Structure of ScSkp1-ScCdc4-pSic1 peptide complex

PDB ID 3v7d

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3v7d"
Personal tools