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3v9k
From Proteopedia
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| - | [[Image:3v9k.png|left|200px]] | ||
| - | + | ==Crystal structure of mouse 1-pyrroline-5-carboxylate dehydrogenase complexed with the product glutamate== | |
| - | + | <StructureSection load='3v9k' size='340' side='right'caption='[[3v9k]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3v9k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V9K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V9K FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.501Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v9k OCA], [https://pdbe.org/3v9k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v9k RCSB], [https://www.ebi.ac.uk/pdbsum/3v9k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v9k ProSAT]</span></td></tr> |
| - | [[3v9k]] is a 2 chain structure with sequence from [ | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AL4A1_MOUSE AL4A1_MOUSE] Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity). | ||
==See Also== | ==See Also== | ||
| + | *[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]] | ||
*[[Pyrroline-5-carboxylate dehydrogenase|Pyrroline-5-carboxylate dehydrogenase]] | *[[Pyrroline-5-carboxylate dehydrogenase|Pyrroline-5-carboxylate dehydrogenase]] | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| - | [[Category: | + | |
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Srivastava | + | [[Category: Srivastava D]] |
| - | [[Category: Tanner | + | [[Category: Tanner JJ]] |
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Current revision
Crystal structure of mouse 1-pyrroline-5-carboxylate dehydrogenase complexed with the product glutamate
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