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3vc0
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Taipoxin beta subunit isoform 1== | |
| + | <StructureSection load='3vc0' size='340' side='right'caption='[[3vc0]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3vc0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oxyuranus_scutellatus_scutellatus Oxyuranus scutellatus scutellatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VC0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VC0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vc0 OCA], [https://pdbe.org/3vc0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vc0 RCSB], [https://www.ebi.ac.uk/pdbsum/3vc0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vc0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PA2HB_OXYSC PA2HB_OXYSC] Heterotrimer: Snake venom phospholipase A2 (PLA2) heterotrimer that acts as a potent presynaptic neurotoxin by blocking synaptic transmission and synaptic vesicle recycling. May act by binding in a calcium-dependent fashion to neurotonal pentraxin-1 (NPTX1) and neurotonal pentraxin-2 (NPTX2), but not to neuronal pentraxin receptor (NPTXR). Also binds to taipoxin-associated calcium binding protein 49 (RCN2), a protein localized in the lumen of endoplasmic reticulum. Monomer (beta chain): Snake venom phospholipase A2 homolog that is neither toxic nor enzymatically active. Does not bind calcium. | ||
| - | + | ==See Also== | |
| - | + | *[[Phospholipase A2 homolog|Phospholipase A2 homolog]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Oxyuranus scutellatus scutellatus]] | ||
| + | [[Category: Beltramini M]] | ||
| + | [[Category: Cendron L]] | ||
| + | [[Category: Micetic I]] | ||
| + | [[Category: Paoli M]] | ||
| + | [[Category: Polverino de Laureto P]] | ||
Current revision
Crystal structure of Taipoxin beta subunit isoform 1
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