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3vdl

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[[Image:3vdl.jpg|left|200px]]
 
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==Crystal structure of circumsporozoite protein aTSR domain, P43212 form==
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The line below this paragraph, containing "STRUCTURE_3vdl", creates the "Structure Box" on the page.
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<StructureSection load='3vdl' size='340' side='right'caption='[[3vdl]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3vdl]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VDL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VDL FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vdl OCA], [https://pdbe.org/3vdl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vdl RCSB], [https://www.ebi.ac.uk/pdbsum/3vdl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vdl ProSAT]</span></td></tr>
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{{STRUCTURE_3vdl| PDB=3vdl | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of circumsporozoite protein aTSR domain, P43212 form===
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[https://www.uniprot.org/uniprot/CSP_PLAF7 CSP_PLAF7] Essential sporozoite protein (PubMed:29554084, PubMed:32150583). In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands (By similarity). In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes (PubMed:29554084, PubMed:32150583). Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes (By similarity).[UniProtKB:P23093]<ref>PMID:29554084</ref> <ref>PMID:32150583</ref> In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.[UniProtKB:P23093]
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== References ==
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<references/>
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 22547819 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Plasmodium falciparum 3D7]]
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{{ABSTRACT_PUBMED_22547819}}
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[[Category: Doud MB]]
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[[Category: Koksal AC]]
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==About this Structure==
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[[Category: Lu C]]
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[[3vdl]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VDL OCA].
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[[Category: Mi LZ]]
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[[Category: Song G]]
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==Reference==
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[[Category: Springer TA]]
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<ref group="xtra">PMID:022547819</ref><references group="xtra"/>
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[[Category: Plasmodium falciparum]]
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[[Category: Doud, M B.]]
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[[Category: Koksal, A C.]]
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[[Category: Lu, C.]]
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[[Category: Mi, L Z.]]
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[[Category: Song, G.]]
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[[Category: Springer, T A.]]
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[[Category: Atsr]]
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[[Category: Cell invasion]]
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[[Category: Tsr]]
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Current revision

Crystal structure of circumsporozoite protein aTSR domain, P43212 form

PDB ID 3vdl

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