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4atj

From Proteopedia

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[[Image:4atj.png|left|200px]]
 
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{{STRUCTURE_4atj| PDB=4atj | SCENE= }}
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==DISTAL HEME POCKET MUTANT (H42E) OF RECOMBINANT HORSERADISH PEROXIDASE IN COMPLEX WITH BENZHYDROXAMIC ACID==
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<StructureSection load='4atj' size='340' side='right'caption='[[4atj]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===DISTAL HEME POCKET MUTANT (H42E) OF RECOMBINANT HORSERADISH PEROXIDASE IN COMPLEX WITH BENZHYDROXAMIC ACID===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4atj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Armoracia_rusticana Armoracia rusticana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ATJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ATJ FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12351824}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BHO:BENZHYDROXAMIC+ACID'>BHO</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4atj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4atj OCA], [https://pdbe.org/4atj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4atj RCSB], [https://www.ebi.ac.uk/pdbsum/4atj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4atj ProSAT]</span></td></tr>
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[[4atj]] is a 2 chain structure of [[Horseradish peroxidase]] with sequence from [http://en.wikipedia.org/wiki/Armoracia_rusticana Armoracia rusticana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ATJ OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PER1A_ARMRU PER1A_ARMRU] Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/at/4atj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=4atj ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Horseradish peroxidase|Horseradish peroxidase]]
*[[Horseradish peroxidase|Horseradish peroxidase]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:012351824</ref><references group="xtra"/>
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[[Category: Armoracia rusticana]]
[[Category: Armoracia rusticana]]
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[[Category: Peroxidase]]
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[[Category: Large Structures]]
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[[Category: Gajhede, M.]]
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[[Category: Gajhede M]]
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[[Category: Henriksen, A.]]
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[[Category: Henriksen A]]
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[[Category: Jennings, S.]]
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[[Category: Jennings S]]
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[[Category: Meno, K.]]
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[[Category: Meno K]]
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[[Category: Smith, A T.]]
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[[Category: Smith AT]]
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[[Category: Heme enzyme]]
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[[Category: Mutant]]
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[[Category: Oxidoreductase]]
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[[Category: Peroxidase]]
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Current revision

DISTAL HEME POCKET MUTANT (H42E) OF RECOMBINANT HORSERADISH PEROXIDASE IN COMPLEX WITH BENZHYDROXAMIC ACID

PDB ID 4atj

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