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4atj

From Proteopedia

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{{Seed}}
 
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[[Image:4atj.png|left|200px]]
 
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==DISTAL HEME POCKET MUTANT (H42E) OF RECOMBINANT HORSERADISH PEROXIDASE IN COMPLEX WITH BENZHYDROXAMIC ACID==
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The line below this paragraph, containing "STRUCTURE_4atj", creates the "Structure Box" on the page.
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<StructureSection load='4atj' size='340' side='right'caption='[[4atj]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[4atj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Armoracia_rusticana Armoracia rusticana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ATJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ATJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BHO:BENZHYDROXAMIC+ACID'>BHO</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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{{STRUCTURE_4atj| PDB=4atj | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4atj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4atj OCA], [https://pdbe.org/4atj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4atj RCSB], [https://www.ebi.ac.uk/pdbsum/4atj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4atj ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PER1A_ARMRU PER1A_ARMRU] Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/at/4atj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=4atj ConSurf].
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<div style="clear:both"></div>
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===DISTAL HEME POCKET MUTANT (H42E) OF RECOMBINANT HORSERADISH PEROXIDASE IN COMPLEX WITH BENZHYDROXAMIC ACID===
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==See Also==
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*[[Horseradish peroxidase|Horseradish peroxidase]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12351824}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 12351824 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12351824}}
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==About this Structure==
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4ATJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Armoracia_rusticana Armoracia rusticana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ATJ OCA].
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==Reference==
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Structural analysis of the two horseradish peroxidase catalytic residue variants H42E and R38S/H42E: implications for the catalytic cycle., Meno K, Jennings S, Smith AT, Henriksen A, Gajhede M, Acta Crystallogr D Biol Crystallogr. 2002 Oct;58(Pt 10 Pt 2):1803-12. Epub, 2002 Sep 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12351824 12351824]
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[[Category: Armoracia rusticana]]
[[Category: Armoracia rusticana]]
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[[Category: Peroxidase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Gajhede M]]
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[[Category: Gajhede, M.]]
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[[Category: Henriksen A]]
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[[Category: Henriksen, A.]]
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[[Category: Jennings S]]
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[[Category: Jennings, S.]]
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[[Category: Meno K]]
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[[Category: Meno, K.]]
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[[Category: Smith AT]]
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[[Category: Smith, A T.]]
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[[Category: Heme enzyme]]
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[[Category: Mutant]]
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[[Category: Oxidoreductase]]
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[[Category: Peroxidase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 13:28:53 2008''
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Current revision

DISTAL HEME POCKET MUTANT (H42E) OF RECOMBINANT HORSERADISH PEROXIDASE IN COMPLEX WITH BENZHYDROXAMIC ACID

PDB ID 4atj

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