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4crx

From Proteopedia

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{{Seed}}
 
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[[Image:4crx.png|left|200px]]
 
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==ASYMMETRIC DNA-BENDING IN THE CRE-LOXP SITE-SPECIFIC RECOMBINATION SYNAPSE==
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The line below this paragraph, containing "STRUCTURE_4crx", creates the "Structure Box" on the page.
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<StructureSection load='4crx' size='340' side='right'caption='[[4crx]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[4crx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_P1 Escherichia virus P1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CRX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CRX FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4crx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4crx OCA], [https://pdbe.org/4crx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4crx RCSB], [https://www.ebi.ac.uk/pdbsum/4crx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4crx ProSAT]</span></td></tr>
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{{STRUCTURE_4crx| PDB=4crx | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RECR_BPP1 RECR_BPP1] Catalyzes site-specific recombination between two 34-base-pair LOXP sites. Its role is to maintain the phage genome as a monomeric unit-copy plasmid in the lysogenic state.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cr/4crx_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=4crx ConSurf].
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<div style="clear:both"></div>
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===ASYMMETRIC DNA-BENDING IN THE CRE-LOXP SITE-SPECIFIC RECOMBINATION SYNAPSE===
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==See Also==
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*[[Resolvase 3D structures|Resolvase 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10377382}}, adds the Publication Abstract to the page
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[[Category: Escherichia virus P1]]
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(as it appears on PubMed at http://www.pubmed.gov), where 10377382 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Gopaul DN]]
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{{ABSTRACT_PUBMED_10377382}}
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[[Category: Guo F]]
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[[Category: Van Duyne GD]]
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==About this Structure==
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4CRX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_p1 Enterobacteria phage p1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CRX OCA].
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==Reference==
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Asymmetric DNA bending in the Cre-loxP site-specific recombination synapse., Guo F, Gopaul DN, Van Duyne GD, Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7143-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10377382 10377382]
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[[Category: Enterobacteria phage p1]]
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[[Category: Single protein]]
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[[Category: Duyne, G D.Van.]]
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[[Category: Gopaul, D N.]]
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[[Category: Guo, F.]]
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[[Category: Cre recombinase]]
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[[Category: Dna bending]]
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[[Category: Protein-dna interaction]]
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[[Category: Recombination]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 13:33:29 2008''
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Current revision

ASYMMETRIC DNA-BENDING IN THE CRE-LOXP SITE-SPECIFIC RECOMBINATION SYNAPSE

PDB ID 4crx

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