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4d9q
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4d9q is ON HOLD Authors: Murray, J.M., Wiesmann, C. Description: Inhibiting Alternative Pathway Complement Activation by Targeting the Exosite on F...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Inhibiting Alternative Pathway Complement Activation by Targeting the Exosite on Factor D== | |
| - | + | <StructureSection load='4d9q' size='340' side='right'caption='[[4d9q]], [[Resolution|resolution]] 2.28Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4d9q]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Macaca_mulatta Macaca mulatta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D9Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D9Q FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d9q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d9q OCA], [https://pdbe.org/4d9q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d9q RCSB], [https://www.ebi.ac.uk/pdbsum/4d9q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d9q ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/F6YBP7_MACMU F6YBP7_MACMU] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Macaca mulatta]] | ||
| + | [[Category: Murray JM]] | ||
| + | [[Category: Wiesmann C]] | ||
Current revision
Inhibiting Alternative Pathway Complement Activation by Targeting the Exosite on Factor D
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